Yes, I removed the dividers to make more room. But, I began to get tired of unpacking everything when we needed just certain items, mainly when we are in a studio or a really short trip.
Now, I have individual boxes, grouped mostly by where it is used. I have a "bathroom" box, kitchen box, snacks, main area (router, notepad, etc), ponchos, etc. I still have the tackle-style box and I tuck a few things around the boxes. Pack-rat that I am, I did have to modify my disappointment that I wasn't using every square inch of space, but it is more than offset by the time saved unpacking and then re-packing at the end of the trip.
Don't be fooled by the pics - I had already started to unpack when I decided to take the pics. Also, our hampers and refillable cups (2) are missing from the picture of the "stuff".